Separating the Wheat from the Chaff: Prediction-Assisted Rescoring of Peptidic Fragment Ion Spectra

The intelligent protein informatics platform Thermo Scientific Proteome Discoverer software Transform proteomics mass spectrometry data into insights Thermo Scientific™ Proteome Discoverer™ software enables comprehensive proteomics data processing workflows empowered by artificial intelligence. • Powerful and flexible framework: Optimized analysis for…

Mass spectrometry Proteome Discoverer 3.0 software with the CHIMERYS intelligent search algorithm comparison to previous strategies, CHIMERYS finds more PSMs Current generation proteomics data analysis tools are unable to per tandem mass spectrum and markedly improves the spectrometers. Tandem mass…

CHIMERYS: An AI-Driven Leap Forward in Peptide Identification Martin Frejno1; Daniel P Zolg1; Tobias Schmidt1; Siegfried Gessulat1; Michael Graber1; Florian Seefried1; Magnus Rathke-Kuhnert1; Samia Ben Fredj1; Shyamnath Premnadh1; Patroklos Samaras1, Kai Fritzemeier2; Frank Berg2; Waqas Nasir2; David Horn3; Bernard Delanghe2;…

The Good, the Bad and the Ugly: when statistics tells you to throw away peptide IDs. Siegfried Gessulat1, Tobias Schmidt2, Michael Graber1, Florian Seefried1, Dave Horn3, Christoph Henrich4, Bernard Delanghe4, Daniel Zolg2, Mathias Wilhelm2, Bernhard Kuster2, Martin Frejno1 1msAId GmbH,…