Determination of collision cross sections of proteins using frequency domain linewidths and time domain decay profile fitting of MS1 data from an Orbitrap mass spectrometer

Extending the mass limit of collision cross sections of proteins in Orbitrap analyzers through kinetic energy and fragmentation behavior analysis Virginia K. James (Presenter)1, James D. Sanders 1, Konstantin Aizikov 2, Kyle Fort 2, Dmitry Grinfeld 2, Alexander Makarov 2,…

Exploring linear sequence determinants of inferred Collisional Cross-Sections of unmodified and phosphorylated peptides in an Orbitrap Mass Analyzer Ulises H. Guzman1, Konstantin Aizikov2, Kyle Fort2, Martin Rykaer1, Jeppe Madsen1, Ana Martinez Del Val1, Alexander Makarov2, Jesper V. Olsen1. 1 2…

Interference of adjacent ion signals in CDMS: the effect on charge accuracy and potential correction algorithms Liangxuan Fu, Michael P. Goodwin, Dmitry Grinfeld, Kyle P. Bowen, Michael W. Senko, Thermo Fisher Scientific, 355 River Oaks Pkwy, San Jose, CA, USA,…

Developments in Orbitrap mass spectrometry on a modified Tribrid mass spectrometer Jesse Canterbury1, Graeme McAlister1, Michael Senko1, Romain Huguet1, Aaron Robitaille1, Arne Kreutzmann2, Konstantin Aizikov2, Dmitry Grinfeld2, and Alexander Makarov2 1Thermo Fisher Scientific, San Jose, California, USA; 2Thermo Fisher Scientific,…