Developments in Real-Time Search on an Orbitrap Tribrid Mass Spectrometer

Use of carry-over models in false-discovery rate filtering in real-time search Jesse Canterbury, William Barshop, Graeme McAlister, and Philip Remes, Thermo Fisher Scientific, San Jose, CA 95134 ABSTRACT Real-time spectral scoring based on FDR Static model carry-over Model continuation Purpose:…

Implementing Comet search engine into Proteome Discoverer to improve TMT Real-Time Search data processing 1 Yang Liu, 2Frank Berg, 1 William D. Barshop, 1Jesse D. Canterbury, 1David Horn, 1David Bergen, 1Romain Huguet, 1Rosa Viner 1Thermo Fisher Scientific, San Jose, CA,…

The intelligent protein informatics platform Thermo Scientific Proteome Discoverer software Transform proteomics mass spectrometry data into insights Thermo Scientific™ Proteome Discoverer™ software enables comprehensive proteomics data processing workflows empowered by artificial intelligence. • Powerful and flexible framework: Optimized analysis for…

APPLICATION NOTE 65729 Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer Authors: Aaron M. Robitaille1, Romain Huguet1, Ryan Bomgarden2, Jesse D. Canterbury1, Daniel Lopez-Ferrer1 Thermo Fisher Scientific, San Jose, CA…