Implementing Comet search engine into Proteome Discoverer to improve TMT Real-Time Search data processing

The intelligent protein informatics platform Thermo Scientific Proteome Discoverer software Transform proteomics mass spectrometry data into insights Thermo Scientific™ Proteome Discoverer™ software enables comprehensive proteomics data processing workflows empowered by artificial intelligence. • Powerful and flexible framework: Optimized analysis for…

Use of carry-over models in false-discovery rate filtering in real-time search Jesse Canterbury, William Barshop, Graeme McAlister, and Philip Remes, Thermo Fisher Scientific, San Jose, CA 95134 ABSTRACT Real-time spectral scoring based on FDR Static model carry-over Model continuation Purpose:…

APPLICATION NOTE 65729 Real-Time Search enables a new gold standard for TMT quantitation accuracy on the Orbitrap Eclipse Tribrid mass spectrometer Authors: Aaron M. Robitaille1, Romain Huguet1, Ryan Bomgarden2, Jesse D. Canterbury1, Daniel Lopez-Ferrer1 Thermo Fisher Scientific, San Jose, CA…

CHIMERYS: An AI-Driven Leap Forward in Peptide Identification Martin Frejno1; Daniel P Zolg1; Tobias Schmidt1; Siegfried Gessulat1; Michael Graber1; Florian Seefried1; Magnus Rathke-Kuhnert1; Samia Ben Fredj1; Shyamnath Premnadh1; Kai Fritzemeier2; Frank Berg2; Waqas Nasir2; David Horn3; Bernard Delanghe2; Christoph Henrich2;…