At line monoclonal antibody analysis using affinity chromatography with mass spectrometry detection and fully compliant data acquisition and processing

Application note | 003310 Biopharma Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS Authors Application benefits Maria Grübner , Kai Scheffler , 1 1 • Heart-cut 2D-LC with protein A affinity chromatography (ProA) of…

Mass spectrometry Perfect fit Orbitrap Exploris MX mass detector Fit for purpose mass detection High-quality mass information offers significant advantages in accelerating biopharmaceutical late-stage development, commercialization, manufacturing, and quality control (QC). This information must be easily and reliably obtained, day…

Application note | 000463 Biopharma The MAM 2.0 workflow enables seamless transition from research and development to quality control Authors Application benefits Hao Yang, Melissa Sato, Royston 1 1 • A MAM method developed on the Thermo Scientific™ Orbitrap Exploris™…

Multi-Attribute Method for batch-to-batch comparison of Etanercept fusion protein Millán-Martín, 1,2Craig Jakes, 1Sara Carillo, 3Jennifer Sutton, 4Julia Kraegenbring, 4Catharina Crone, 5Kai Scheffler, 1,2Jonathan Bones 1 Characterisation and Comparability Laboratory, National Institute for Bioprocessing Research and Training, Dublin, Ireland; 2 School…