Software development for improved sensitivity of massspectrometry-based thermal shift assays (MS-TSA) for target engagement and drug discovery

Experimental Strategies to Improve Drug-target Identification in Mass Spectrometry-based Thermal Stability Assays 1,2 Phaneuf , 1 Figueroa-Navedo , 3 Aizikov , 3 Grinfeld , 3 Kreutzmann , Clifford Amanda M. Konstantin Dmitry Arne 3 3 2 2 3 1 Daniel…

Technical note | 004325 Proteomics High-throughput plasma proteomics for translational biomarker discovery using PreOmics sample preparation and the Orbitrap Astral mass spectrometer Authors Goal Jared Deyarmin¹, Qingling Li¹, Evaluate and compare the analytical performance of PreOmics™ sample preparation kits Jana…

Thermo Proteome Discoverer User Guide Software Version 2.2 XCALI-97808 Revision A June 2017 © 2017 Thermo Fisher Scientific Inc. All rights reserved. Proteome Discoverer, Orbitrap Elite, LTQ Velos, and Q Exactive are trademarks; and LTQ, Orbitrap, Orbitrap Fusion Lumos, Thermo…

Xiaoyue Jiang1, Tabiwang Arrey2, Eugen Damoc2, Michaela Scigelova2, David Horn1, Rosa Viner1, and Andreas F.R. Huhmer1 1 Thermo Fisher Scientific, San Jose, CA, USA; 2Thermo Fisher Scientific, Bremen, Germany Key Words Q Exactive Plus, Q Exactive HF, TMT, Proteome Discoverer…