Rapid Desalting of Proteins for Direct Infusion Intact Mass Analysis using an Optimized SEC Tip

Precise Characterization of Intact Monoclonal Antibodies by the Agilent 6545XT AdvanceBio LC/Q-TOF Application Note Author Introduction David L. Wong Monoclonal antibodies (mAbs) are a very important class of biopharmaceutical molecules. As a protein drug, thorough characterization of the mAb is…

Application Note Pharma & Biopharma Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS Author David L. Wong Agilent Technologies, Inc. Abstract Native mass spectrometry can be used for a variety of protein-based applications, such as protein-protein interaction, protein-ligand…

Agilent-NISTmAb Intact & Subunit Analysis Using Reversed Phase Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…

Procedures Analysis of Intact Monoclonal Antibodies Using an M3 MicroLC with the TripleTOF® 6600 Robust and Sensitive Workflow for Qualitative and Quantitative Analysis of Biotherapeutic IgGs Khatereh Motamedchaboki, Remco van Soest, Daniel Warren and Jenny Albanese SCIEX, USA Overview Key…