Using Ion Mobility to separate different designer drug metabolites

High-throughput experimentation reaction monitoring and analysis of chemistry synthesis products with ultrahigh-throughput 4D timsTOF fleX MALDI-2 technology MALDI mass spectrometry is uniquely suited for high-throughput experimentation (HTE) chemical reaction monitoring by coupling it with trapped ion mobility spectrometry (TIMS) on…

Trapped Ion Mobility Mass Spectrometry is able to resolve minor size differences in supramolecular structures Ion Mobility Mass Spectrometry has started to spread from analytical and omics research fields to other areas, including supramolecular chemistry. Abstract Besides its power to…

Intensity (arb. unit) 132% 0% 100% PS 38:1 m/z 816.5747 ± 0.0122 1/K0 1.433 ± 0.01 Intensity (arb. unit) Mobility [1/K0] 136% 0% 100% PE 20:1_22:6 m/z 816.5517 ± 0.0122 1/K0 1.404 ± 0.01 m/z 1 mm CCS-aware SpatialOMx® enables…

ASMS 2025 WP 097 prio-PASEF: Precision and Discovery in MetID Workflows Beixi Wang1; Xuejun Peng1; Jonathan R. Plante2; Reena G. Patel2; Kyle P. Mummau2; Elke S. Perloff2; Melvin Blaze2; Heiko Neuweger3; Erica Forsberg1 Results (a) prio-PASEF of Testosterone 1Bruker Scientific…