High Resolution and Rapid Peptide Mapping of Monoclonal Antibody Using an Agilent 1290 Infi nity UHPLC and an Agilent 6550 iFunnel Q-TOF LC/MS System

An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies Application Note Biotherapeutics and Biosimilars Authors Introduction David L. Wong Monoclonal antibodies (mAbs) represent one of the fastest growing classes of drugs in the pharmaceutical industry. As a protein drug, the…

Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…

Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF Application Note Authors Introduction David L. Wong Monoclonal antibodies (mAbs) comprise a rapidly growing group of protein-based biomolecules being researched. Due to the heterogeneous nature of protein drugs, extensive analytical…

Mapping the Drug Conjugation Sites of an Antibody-Drug Conjugate Using Automated Sample Preparation and LC/MS Analysis Application Note Authors Introduction Jing Chen Antibody drug conjugates (ADCs) that combine the specificity of monoclonal antibodies (mAbs) with the potency of cytotoxic molecules…