mAb Subunit Analysis Using the SYNAPT XS High Resolution Mass Spectrometer

Application Note INTACT Mass™ - a Versatile waters_connect™ Application for Rapid Mass Confirmation and Purity Assessment of Biotherapeutics Henry Shion, Patrick Boyce, Scott J. Berger, Ying Qing Yu Waters Corporation Abstract In recent years, liquid chromatography-mass spectrometry (LC-MS) intact mass…

Application Note Multi-Reflecting Time of Flight-MS: A Novel Technology for In-depth mAb Subunit Characterization Jonathan Fox, Ying Qing Yu, Scott J. Berger, Nick Pittman Waters Corporation Application Brief This is an Application Brief and does not contain a detailed Experimental…

[ PRODUCT SOLUTION ] Enhanced biopharmaceutical characterization using the SELECT SERIES™ MRT INTRODUCTION Today, an ever-increasing number of approved therapeutics fall into the biologics class. As this number grows so do the requirements of the analytics used to characterize and…

Top-down Monoclonal Antibody (mAb) Analysis Using CID and ETD Fragmentation and the UNIFI Scientific Information System Min Du,1 Martin DeCecco,2 Henry Shion,1 Laetitia Denbigh2 1 Waters Corporation, Milford, MA, USA, 2 Waters Corporation, Wilmslow, UK A P P L I…