Quantification of Polysorbate Using the ACQUITY UPLC H-Class Bio System with ELS Detection

Application Note Comparing ELSD and CAD Performance on Polysorbate Quantification in Infliximab Drug Products Duanduan Han, Robert E. Birdsall, Jennifer Simeone, Michael Fogwill, Ying Qing Yu Waters Corporation Abstract This application note reports a baseline subtraction processing method in Empower…

ELSD Performance on Polysorbate Quantification in Infliximab Drug Products Duanduan Han, Robert Birdsall, Jennifer Simeone, Michael Fogwill, Ying Qing Yu Waters Corporation, Milford, MA INTRODUCTION Polar head-group METHODS Principles of evaporative light scattering Hydrophobic ester tail Step 3: Detection PS80…

Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2D Part 1 of 3: On-line Desalting of Biotherapeutic Samples for Increased Productivity Robert Birdsall, Sean M. McCarthy, and Weibin Chen Waters Corporation, Milford, MA, USA A P P L I C…

Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2D Part 3 of 3: On-line Enrichment of Low Abundance Species Robert Birdsall, Vera Ivleva, Sean M. McCarthy, and Weibin Chen Waters Corporation, Milford, MA, USA A P P L I C…