Single-Use and High-Throughput HILIC SPE Device Formats and an IgG Control Standard for Facilitating N-Glycan Analyses

GlycoWorks Sample Preparation Consumables Glycosylation is one of the most common forms of post-translational modification (PTM) of human and other eukaryotic proteins. Glycosylated proteins (glycoproteins) make up 50–70% of human proteins. Consequently, glycans play a critical role in a myriad…

Optimization of GlycoWorks HILIC SPE for the Quantitative and Robust Recovery of N-Linked Glycans from mAb-Type Samples Matthew A. Lauber, Stephan M. Koza, and Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I…

Rapid Preparation of Released N-Glycans for HILIC Analysis Using a Novel Fluorescence and MS-Active Labeling Reagent Matthew A. Lauber,1 Darryl W. Brousmiche,1 Zhengmao Hua,1 Stephan M. Koza,1 Ellen Guthrie,2 Paula Magnelli,2 Christopher H. Taron,2 Kenneth J. Fountain1 1 Waters Corporation,…

GlycoWorks Sample Preparation Protocol For MALDI The GlycoWorks™ HILIC μElution Plate is ideal for removing contaminants like salts and detergents from hydrophilic analytes, such as carbohydrates, prior to mass spectrometry analysis. It enables elution volumes as low as 25 μL,…