Stability and Performance of Cyano Bonded Phase HPLC Columns for Reversed-Phase, Normal-Phase and HILIC Applications

Grouping Modern HPLC Columns Into Chemical Classes for Improving Phase Selection and Method Development Richard A. Henry, Hillel K. Brandes, William H. Campbell, Carmen T. Santasania, and David S. Bell Supelco, Div. of Sigma-Aldrich, Bellefonte, PA 16823 USA www.sigma-aldrich.com T410088…

Troubleshooting Liquid Chromatographic Separations: Avoiding Common Issues through Informed Method Development Practices Dave S. Bell Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA sigma-aldrich.com/analytical T414096 © 2014 Sigma-Aldrich Co. All rights reserved. Objective •Most of the difficult problems encountered are…

Multi-Dimensional LC/MS Using Orthogonal Reversed-Phase Stationary Phases David S. Bell and Shawn R. Wyatt Supelco 595 North Harrison Road, Bellefonte, PA 16823 T403167 GIL Outline • Introduction - What is multi-dimensional chromatography? - Molecular interactions • Methods using multi-dimensional chromatography…

Transfer and Speed-up of Methods to Fused-Core Particle Columns – EPA Method 1694 Ed Mauney, Hillel K. Brandes, William H. Campbell, Wayne K. Way, Richard A. Henry, David S. Bell, and Carmen T. Santasania Supelco, Div. of Sigma-Aldrich, Bellefonte, PA…