HPLC Column Comparison Screening Study for Reversed Phase Columns

HPLC Column Comparison Screening Study for Reversed Phase Columns Carmen T. Santasania, Eric M. Snyder, Matilal Sarker, and Tracy L. Ascah Supelco, 595 North Harrison Road, Bellefonte, PA 16823, USA T403058 2 Introduction When developing a new HPLC method, selecting…

595 North Harrison Road Bellefonte, PA 16823-0048 USA Telephone 800-247-6628 • 814-359-3441 Fax 800-447-3044 • 814-359-3044 email: supelco@s ial.com sigma-aldrich.com/supelco Bulletin 937 Use Discovery to Reduce HPLC Method Development Time Following the Discovery method development protocol and using the Column…

Multi-Dimensional LC/MS Using Orthogonal Reversed-Phase Stationary Phases David S. Bell and Shawn R. Wyatt Supelco 595 North Harrison Road, Bellefonte, PA 16823 T403167 GIL Outline • Introduction - What is multi-dimensional chromatography? - Molecular interactions • Methods using multi-dimensional chromatography…

Troubleshooting Liquid Chromatographic Separations: Avoiding Common Issues through Informed Method Development Practices Dave S. Bell Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA sigma-aldrich.com/analytical T414096 © 2014 Sigma-Aldrich Co. All rights reserved. Objective •Most of the difficult problems encountered are…