Sigma-Aldrich Integrated Chiral Services

Application Note Identifying a diastereomeric salt for a challenging chiral resolution Advancing a therapeutic for malaria using the Big Kahuna system MMV used Unchained Lab’s high-throughput techniques to deliver successful results in approximately two weeks to a problem that they…

Basics of Chiral HPLC Definitions Principles Available CSPs Mobile phase types T408109 sigma-aldrich.com The Field of Stereochemistry 1. All isomers have same chemical formula but differ in the arrangement of certain chemical groups in space. 2. Many types of isomers…

Astec® CHIRALDEX® and Supelco® DEX™ Chiral GC Columns The Widest Variety of Derivatized Cyclodextrins Stable, Derivatized Cyclodextrinbased Chiral GC Phases Twenty-four Different Phases Surface-interaction as well as Inclusion-dominant Phases Supelco® Chiral GC Columns Chiral GC Columns from Sigma-Aldrich® Gas chromatography…

Application Note High-throughput 96-well cocrystal screening workflow for active pharmaceutical ingredients Increasingly, poorly soluble drug candidates are entering development, which has made identifying and selecting stable solid forms of an active pharmaceutical ingredient (API) with enhanced in vivo absorption more…