Sensitive and Reproducible LC-MS Quantification of C-Reactive Protein in Plasma: A Potential Biomarker of Inflammation

SENSITIVE AND REPRODUCIBLE LC-MS QUANTIFICATION OF C-REACTIVE PROTEIN IN PLASMA FOR CLINICAL RESEARCH Paula Orens, Mary Lame, Steven Calciano, and Erin Chambers Waters Corporation 34 Maple Street Milford, MA 01757 RESULTS INTRODUCTION Curve (µg/mL) Weighting Linear Fit (R2) % Accuracy…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…

[ APPLICATION NOTE ] Automated, Kit-Based Sample Preparation Strategy for LC-MS Quantification of Cetuximab in Rat Plasma Paula Orens, Mary Lame, and Steven Calciano Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Automated and standardized approach In 2015, the global…

[ APPLICATION NOTE ] Amyloid Beta Peptides Quantification by SPE-LC-MS/MS with Automated Sample Preparation for Preclinical Research and Biomarker Discovery Jaime Salcedo, 1 Philip Lambert,1 Leanne Davey,1 Mary Lame, 2 Caitlin Dunning, 2 Erin Chambers 2 Waters Corporation, Wexford, Ireland;…