Automated, Kit-Based Sample Preparation Strategy for LC-MS Quantification of Cetuximab in Rat Plasma

[ APPLICATION NOTE ] Quantification of Rituximab in Plasma Using an Automated and Standardized Kit-Based Approach Mary Lame, Paula Orens, and Steven Calciano Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Automated and standardized approach In the past decade, monoclonal…

[ APPLICATION NOTE ] Accurate and Sensitive LC-MS/MS Quantification of Adalimumab in Serum/Plasma: Impact of Sample Preparation on Method Performance Caitlin Dunning, Mary Lame, Steven Calciano, and Kelly Doering Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Speed and…

AUTOMATED SAMPLE PREPARATION FOR HYBRID LC-MS/MS PROTEIN QUANTIFICATION Paula Orens and Mary Lame Waters Corporation, 34 Maple St Milford, MA 01757 INTRODUCTION METHODS Sample Preparation Whole Plasma Samples Using the Waters ProteinWorks™ (ProteinWorks) Auto-eXpress Direct Digest and µElution SPE CleanUp…

[ TECHNOLOGY BRIEF ] Automated and Standardized, Kit-Based Workflow for Protein Quantification Mary Lame, Paula Orens, and Steven Calciano Waters Corporation, Milford, MA, USA Bottom-up, protein quantification workflows are time consuming and complex. A need exists for simpler and standardized…