Process Monitoring of Monoclonal Antibody Subunits for Fast, Critical Quality Attribute Monitoring Using the ACQUITY QDa Detector

Application Note Process Monitoring of Monoclonal Antibody Subunits for Fast, Critical Quality Attribute Monitoring Using the ACQUITY QDa Detector Brooke M. Koshel, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract In this work, we demonstrate the applicability of the…

Application Note Pharma & Biopharma Critical Quality Attribute Monitoring of mAbs at the Intact and Subunit Levels Using a Cost-Effective, Simple and Robust LC/MS Solution Authors Linfeng Wu, Lisa Zang, and Guannan Li Agilent Technologies, Inc. Abstract Recombinant monoclonal antibodies…

APPLICATION NOTE 73885 Complete characterization of monoclonal antibodies under native and denaturing conditions Kristina Srzentić1, Eugen Damoc2, Kai Scheffler3, Tom Buchanan4, Krisztina Radi4, Jennifer Sutton1 Thermo Fisher Scientific, 1 Cambridge, Massachusetts, US 2 Bremen, Germany 3 Germering, Germany 4 Hemel…

APPLICATION NOTE 72854 Antibody subunit analysis workflow on a quadrupole-Orbitrap mass spectrometer: from optimized sample preparation to data analysis Authors Kai Scheffler, Thermo Fisher Scientific, Germering Eugen Damoc, Thermo Fisher Scientific, Bremen Keywords Antibody subunits, Orbitrap, Q Exactive BioPharma, sample…