High Throughput DESI Imaging for Optimized Analysis of Biological Tissues

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

[ TECHNOLOGY BRIEF ] An Improved Workflow for DESI Imaging Mass Spectrometry Incorporating Waters High Definition Imaging Software Emrys Jones and Emmanuelle Claude New software acquisition approach streamlines DESI imaging workflow to maximize data acquisition. GOAL Here we describe improvements…

[ TECHNOLOGY BRIEF ] Ion Mobility Separation Coupled With Desorption Electrospray Ionization Mass Spectrometry for High Specificity MS Imaging Emmanuelle Claude Desorption Electrospray Ionization (DESI) imaging directly from tissue section, followed by gas phase separation of molecules using ion mobility…

Utility of Desorption Electrospray Ionization (DESI) for Mass Spectrometry Imaging Emmanuelle Claude and Emrys Jones G OA L DESI imaging provides effective and meaningful To describe the DESI imaging technique as applied to mass spectrometry imaging using time-of-flight (TOF) mass…