Ion Mobility Separation Coupled With Desorption Electrospray Ionization Mass Spectrometry for High Specificity MS Imaging

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

COLLISION CROSS SECTION ENABLED DESI ION MOBILITY MASS SPECTROMETRY IMAGING Anthony J. Midey, Hernando J. Olivos, and Bindesh Shrestha Waters Corp., Beverly, MA INTRODUCTION Mass spectrometry imaging (MSI) determines the localization of compounds on samples, including tissue sections and drug…

Lipidomic Imaging of isobaric lipids using high‐resolution ion mobility mass spectrometry with DESI XS Bindesh Shrestha,1 Mark Towers,2 Hernando Olivos,1 Anthony Midey,1 and Emmanuelle Claude2 1 Waters Corporation, Milford, MA, USA 2 Waters Corporation, Wilmslow, UK INTRODUCTION  Desorption electrospray…

Spatial distribution of isobaric lipids using high-resolution ion mobility with the DESI XS Bindesh Shrestha,1 Mark Towers,2 Hernando Olivos,1 Anthony Midey,1 and Emmanuelle Claude2 1 Waters Corporation, Milford, MA, USA 2 Waters Corporation, Wilmslow, UK INTRODUCTION • Desorption electrospray ionization…