Advantages of Ion Mobility for MALDI Imaging of N-glycans from Tumor Bearing FFPE Tissue in Clinical Research

MALDI FTMS Imaging Mass Spectrometry of N-glycans as Tissue Biomarkers of Cancer In this application note, we describe preparation and imaging analysis of N-glycans from formalin-fixed paraffin embedded (FFPE) tissues using the solariX MALDI FTMS. N-glycosylation is a common post…

MALDI-2 for enhanced in situ N-glycan analysis N-glycans are important players in a variety of pathologies including different types of cancer, (auto)immune diseases, and also viral infections. Abstract Matrix-assisted laser desorption/ ionization mass spectrometry (MALDI-MS) is an important tool for…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…

[ TECHNOLOGY BRIEF ] Ion Mobility Separation Coupled With Desorption Electrospray Ionization Mass Spectrometry for High Specificity MS Imaging Emmanuelle Claude Desorption Electrospray Ionization (DESI) imaging directly from tissue section, followed by gas phase separation of molecules using ion mobility…