Advantages of using ACQUITY PREMIER System and Columns with MaxPeak HPS Technology for Bioanalysis of Gefitinib – an EGFR Inhibitor

Application Note Improvements in Sensitivity for Quantification of Steroid Phosphate Drugs Using ACQUITY PREMIER and MaxPeak HPS Columns Nikunj Tanna, Robert S. Plumb, Lauren Mullin Waters Corporation Abstract Analytes with electron rich moieties such as phosphate and carboxylate groups are…

MaxPeak Premier Columns Small Molecule Application Notebook CONTENTS Introduction Non-Specific Adsorption: Unwanted Interactions................................................................................... 3 How Do Scientists Solve This Problem Today?......................................................................................... 4 Precision Chemistry for Particles and Surfaces........................................................................................ 5 Fundamentals Waters™ Premier Standards to Investigate the Inertness of Chromatographic Systems....................................................................................................................................7…

Application Note Improving Released N-glycan Analysis in Biotherapeutic Development Using the ACQUITY Premier Solution with MaxPeak High Performance Surfaces (HPS) Technology Ximo Zhang, Jacob Kellett, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Characterization and monitoring of glycosylation are…

IMPROVEMENTS IN SENSITIVITY FOR BIOANALYSIS OF WARFARIN USING ACQUITY™ PREMIER UPLC SYSTEM AND XEVO™ TQ ABSOLUTE TANDEM QUADRUPOLE MASS SPECTROMETER Authors: Nikunj Tanna, Rob Plumb, and Steven Lai Affiliations: Waters Corporation, Milford, MA, USA INTRODUCTION METHODS RESULTS & DISCUSSION Bioanalysis…