Agilent G4243A 2D-LC ASM Valve Guide - Technical Note

Technical Overview The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation Achieving Improved Resolution and Sensitivity for Challenging Combinations of Separation Conditions Author Sonja Krieger Agilent Technologies, Inc. Abstract A major challenge during method development in two-dimensional liquid chromatography (2D-LC)…

Application Note Pharma and Biopharma Analysis of Peptone Samples Using the Agilent InfinityLab 2D‑LC Solutions with Active Solvent Modulation Authors Gerd Vanhoenacker, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) President Kennedypark 26 B-8500 Kortrijk Belgium Sonja Krieger,…

Application Note Biopharma/Pharma Determination of Multiple Attributes of Monoclonal Antibodies Simultaneous and parallel multi-attribute analysis using 3D-LC/MS with 2D multimethod option mAb SEC Size variants Protein A CEX LC/MS mAb Titer Charge variants Mol wt (MW) AA sequence PTM Cell…

Technical Overview Analysis of Peptide/Protein*-Related Impurities Using the Integrated Solution of Bio 2D-LC/Q-TOF in Agilent MassHunter Software Response units (%) ×102 1 0 D 2 16 17 18 1 D Acquisition time (min) 2.0 2.4 2.8 2 D Acquisition time…