Instrument Mixer Considerations to Improve Assay Reproducibility and Sensitivity

Application Note Ion-Pairing Selection and Mixer Considerations in the Development of LCMS Workflows Robert E. Birdsall, David Dao, Brooke M. Koshel, Ying Qing Yu Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract…

Application Note Peptide Mapping using Binary Biocompatible LC Systems: Evaluation of Retention Time Precision and Mixing Effects on Waters and Competitive LCs Jennifer Simeone, Paula Hong Waters Corporation Abstract A fully biocompatible LC system equipped with binary high-pressure mixing solvent…

Application Note Improved Sensitivity for Trifluoroacetic Acid Gradients on the Alliance™ iS HPLC Systems Kimberly Martin, Lise Gauthier, Paula Hong Waters Corporation Abstract Given the nature of biomolecules, such as amino acids and peptides, many HPLC reversed phase bioseparations often…

Application Note Monitoring Impurities Using a High Throughput Focused Gradient With the Alliance™ iS Bio System Duanduan Han, Robert E. Birdsall, Karen Nyholm Waters Corporation Abstract The Alliance iS Bio HPLC System provides an efficient HPLC platform for routine monitoring…