Interpreting MS Spectra Acquired Within Empower 3 Using the ACQUITY QDa Mass Detector

ADDING COST EFFECTIVE MASS DETECTION FOR IMPROVED PRODUCTIVITY IN OLIGONUCLEOTIDE SCREENING ASSAYS Robert E. Birdsall, Sean M. McCarthy, Scott J. Berger, Maki Terasaki, Kenji Hiroseand Ying Qing Yu Biopharmaceutical Business Team, Waters Corporation, Milford, MA and Tokyo, Japan TUV Absorbance…

High-throughput Screening of Oligonucleotides for Identity and Purity Assessment Using the ACQUITY QDa Detector and ProMass for MassLynx Robert E. Birdsall and Ying Qing Yu Waters Corporation, Milford, MA, USA A P P L I C AT I O N…

[ APPLICATION NOTEBOOK ] ACQUITY QDa Detector QC APPLICATIONS COMPENDIUM EDITION 2 Dear Colleague The 2013 introduction of the ACQUITY™ QDa™ Detector was a breakthrough in Chromatography and Mass Spectrometry integration. It was the fulfilment of a vision 20 years…

[ APPLICATION NOTE ] Developing a Novel, Integrated LC-MS Workflow for High-resolution Monitoring and Characterization of Oligonucleotides Henry Shion, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Optimized RP-UPLC mobile phase Methods that…