James Little - Mass Spec Interpretation Services
James Little - Mass Spec Interpretation Services

My name is James Little and my private consulting company is Mass Spec Interpretation Services. I contract for NIST, Wiley, and Sapec. Previously, I was a Research Fellow specializing in mass spectrometry at Eastman Chemical Company in Kingsport, TN and retired in early 2016 after >37 years of service. For 2017-2019, I did NMR as a limited service employee specializing in end group determinations for Eastman.

My main interest is the identification of organic compounds by mass spectrometry in organic mixtures. All the technical information on my web page was approved as technical session handouts, conference presentations, workshops, journal publications, courses, etc. for distribution outside Eastman. Other postings on this site are my own and do not necessarily represent Eastman’s positions, strategies or opinions. I also include a “little” information about my sailing experiences.

In 2017, I purchased a used Model S85 Tesla and starting to participate in electric vehicle events. In addition, I am a member of the choir at St. Paul’s Episcopal Church, play competitive duplicate bridge, and race sailboats on Watauga Lake.

 

News

Sending MS/MS (Tandem) Spectra to NIST26 Search
Article | Academy

Sending MS/MS (Tandem) Spectra to NIST26 Search

Learn how to send MS/MS spectra directly from Agilent, Waters, Thermo, and other vendor software to NIST26 for fast library searching without full chromatogram processing.
Creating MS/MS User Libraries in NIST26
Article | Academy

Creating MS/MS User Libraries in NIST26

Learn how to create custom MS/MS user libraries in NIST26, add structures and metadata, manage high- and low-resolution spectra, and improve laboratory-specific compound identification.
 

Wrote about us

News from LabRulezGCMS Library - Week 43, 2024
Article | Application

News from LabRulezGCMS Library - Week 43, 2024

This week we bring you applications by Agilent Technologies, Thermo Fisher Scientific, and Shimadzu and a presentation by James Little - Mass Spec Interpretation Services!
News from LabRulezLCMS Library - Week 42, 2024
Article | Application

News from LabRulezLCMS Library - Week 42, 2024

We bring you posters, presentations, applications, and other documents by Thermo Fisher Scientific, Agilent Technologies, Shimadzu, Waters Corporation, and James Little Mass Spec Interpretation Services!
 

Library

Open paper Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications

Using NIST MS Search with Agilent OpenLab Software for Unknown Identifications

Instrumentation
Software, LC/MS, GC/MSD
Manufacturer
Agilent Technologies
Industries
Open paper Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)

Changes in Tandem (MS/MS) NIST23 Search Program (V3.0)

Instrumentation
Software
Manufacturer
Industries
Open paper NIST/EPA/NIH EI-MS LIBRARY (2023 Release)

NIST/EPA/NIH EI-MS LIBRARY (2023 Release)

Instrumentation
Software
Manufacturer
Wiley
Industries
Open paper NIST Tandem Mass Spectral Library (2023 Release)

NIST Tandem Mass Spectral Library (2023 Release)

Instrumentation
Software
Manufacturer
Wiley
Industries