Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
LCMSArticle | Science and research

Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability

How can laboratories modernize legacy HPLC methods while remaining compliant? Learn how Opella leveraged UHPLC and evolving regulatory guidance to boost productivity.
Modernizing Routine HPLC Methods: Aligning Productivity, Compliance, and Sustainability
Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
LCMSScientific article | Science and research

Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

This study identifies N-lactoyl-amino acids as plasma biomarkers that accurately reflect metformin exposure and treatment adherence in T2D.
Untargeted Metabolomics Identifies N-Lactoyl-Amino Acids as Dose-Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
LCMSArticle | Science and research

Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS

How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids
LCMSArticle | Science and research

How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids

Automated in-needle amino acid derivatization for HPLC-FLD reduces sample preparation time, improves reproducibility, and minimizes manual laboratory work.
How to Cut HPLC Sample Preparation Time for Derivatizing Amino Acids
Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions
GCMSLCMSArticle | Science and research

Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions

Expert insights from Thermo Fisher and SampleQ on MOSH/MOAH analysis using LC-GC-FID and GC×GC-FID/MS. Practical guidance on sample preparation, ISO 20122, internal standards, and data workflows.
Ask the Experts: Practical Answers to Today’s Biggest MOSH/MOAH Analysis Questions
Boosting Productivity in Toxicology Labs
LCMSArticle | Application

Boosting Productivity in Toxicology Labs

How do you boost toxicology productivity without sacrificing sensitivity? LC-MS/MS workflows enable rapid analysis of a broad range of drugs in 5–7 minutes.
Boosting Productivity in Toxicology Labs
Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization
LCMSScientific article | Science and research

Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization

This study couples LC to ESI-Orbitrap MS for stable isotope analysis using peak homogenization to remove chromatographic isotope effects and amount dependency, achieving precise C, N, and S isotopologue ratios.
Coupling Liquid Chromatography to Orbitrap Isotope Ratio Mass Spectrometry: Overcoming Isotope Effects of Chromatography and Amount-Dependency by Peak Homogenization
Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering
LCMSScientific article | Science and research

Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering

LC-HRMS screening combined with temporal clustering identified daily domestic discharge patterns in wastewater, enabling improved interpretation of population chemical exposure.
Exploring Domestic Discharge Patterns in Wastewater through LC-HRMS Screening and Temporal Clustering
A Greener HPLC Guide: How ACT Labels Help Promote Lab Sustainability
LCMSArticle | Environment

A Greener HPLC Guide: How ACT Labels Help Promote Lab Sustainability

Labs consume up to 10× more energy than offices. Learn how greener HPLC practices and ACT labels can cut waste, reduce emissions, and support sustainable lab operations.
A Greener HPLC Guide: How ACT Labels Help Promote Lab Sustainability
MOSH/MOAH Analysis: Technology, Regulation, and the Road Ahead
GCMSLCMSArticle | Science and research

MOSH/MOAH Analysis: Technology, Regulation, and the Road Ahead

MOSH/MOAH testing is becoming a key topic in food safety and regulation. Discover how Thermo Fisher Scientific’s LC-GC-FID and GC×GC-MS workflows improve reliability, compliance, and source identification.
MOSH/MOAH Analysis: Technology, Regulation, and the Road Ahead