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Phosphorylation, ADMA, and O-GlcNAc Analysis on the Orbitrap Excedion Pro Mass Spectrometer
Explore how the Orbitrap Excedion Pro MS combines HCD and EThcD fragmentation to improve PTM coverage and site localization for phosphorylation, ADMA, and O-GlcNAc.
Electrospray 101: What to Know About LC-MS Sources – and a First Look at Optispray
Discover how ion sources shape LC-MS performance and why electrospray transformed modern mass spectrometry. Explore EASY-Spray™, NanoSpray Flex™, and the new OptiSpray™ technology.
Exploring a Versatile LC–HRMS Strategy for NDSRI Determination in Beta Blocker Drug Substances
A single LC-HRMS method for NDSRI quantitation across six beta blockers. Discover how Orbitrap MS enables sensitive, robust analysis of trace nitrosamine impurities.
Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS
How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.
Sharper, Faster, Smarter: HRAM Orbitrap Mass Spectrometry Meets Postmortem Toxicology
HRAM Orbitrap LC-MS accelerates postmortem toxicology, enables retrospective screening for emerging drugs, and improves confidence in complex sample analysis.
Fragment Smarter, See Deeper: How the Orbitrap Excedion Pro Unlocks EASY-ETD and HCD Fragmentation
Thermo Fisher Scientific showcases how Orbitrap Excedion Pro combines EASY-ETD and HCD to deliver deeper insight into proteomics, biopharma, and structural biology workflows.
News from LabRulezLCMS Library - Week 16, 2026
This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!
Discover. Innovate. Exceed. — Introducing the Thermo Scientific Orbitrap Excedion Pro Mass Spectrometer
Orbitrap Excedion Pro sets a new standard in MS performance, combining high resolution, sensitivity, and flexibility for analysis from small molecules to proteins.
From Complexity to Clarity: Smarter PFAS Identification Workflows in Compound Discoverer Software
Non-targeted PFAS analysis using Orbitrap HRAM and Compound Discoverer 3.5 enables confident identification of thousands of PFAS through advanced libraries, scoring tools and visualization workflows.
Identification of Substructures in Unknowns Through MSn Data
How MSⁿ spectral libraries like mzCloud help identify substructures in unknown compounds. Learn how fragmentation data can guide structure elucidation and support identification of complex molecules.
