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Comprehensive investigation of matrix effect evaluation approaches for reliable quantification in bioanalysis using UHPLC-MS/MS
A systematic UHPLC-MS/MS study shows that matrix-effect estimates based only on calibration slopes can be biased and introduces an intercept-based correction.
News from LabRulezLCMS Library - Week 10, 2026
This week we bring you application notes by KNAUER, Shimadzu, Thermo Fisher Scientific and Waters Corporation and technical note by Agilent Technologies!
Profiling of free fatty acids in wort using an isolator column-assisted LC-MS/MS approach
The study develops an LC-MS/MS method with isolator column and SPE for accurate FFA profiling in wort, aiming at improved efficiency and application in beer quality studies.
