How to Select the Right SEC Column for the Analysis of Biologics
LCMSArticle | Academy

How to Select the Right SEC Column for the Analysis of Biologics

How to select the right SEC column for biologics? A practical guide based on molecule size, shape, pore size selection, and application range.
How to Select the Right SEC Column for the Analysis of Biologics
Improving Oligonucleotide Conjugate Recovery with Clarity XRO
LCMSArticle | Academy

Improving Oligonucleotide Conjugate Recovery with Clarity XRO

Improve oligonucleotide recovery with Clarity™ XRO. Learn how optimized lysis, SPE conditions, and elution strategies enhance reproducibility and performance in complex biological samples.
Improving Oligonucleotide Conjugate Recovery with Clarity XRO
Magnetic Bead-Based Protein Purification: A Faster and More Efficient Workflow
LCMSArticle | Academy

Magnetic Bead-Based Protein Purification: A Faster and More Efficient Workflow

Magnetic bead-based protein purification enables fast, efficient cleanup without centrifugation, improving reproducibility and supporting high-throughput workflows.
Magnetic Bead-Based Protein Purification: A Faster and More Efficient Workflow
Trimming a GC Column: Purpose, Symptoms, and Proper Technique
GCMSArticle | Academy

Trimming a GC Column: Purpose, Symptoms, and Proper Technique

GC column trimming helps resolve contamination, ghost peaks, baseline instability, and peak tailing. Learn key symptoms and the correct technique for proper column cutting.
Trimming a GC Column: Purpose, Symptoms, and Proper Technique
How to Choose GC Column Dimensions
GCMSArticle | Academy

How to Choose GC Column Dimensions

Guidance on selecting key GC column parameters — length, internal diameter, and film thickness — and their influence on resolution, retention, run time, and sample capacity.
How to Choose GC Column Dimensions
Stop Using C18 for Polar Analytes
LCMSArticle | Academy

Stop Using C18 for Polar Analytes

Why avoid C18 for polar analytes? Overview of HILIC principles, mobile phase composition, gradient strategy, pH testing, and practical tips.
Stop Using C18 for Polar Analytes
Why Is It Necessary to Dry the SPE Sorbent Before Elution?
GCMSLCMSArticle | Academy

Why Is It Necessary to Dry the SPE Sorbent Before Elution?

Proper drying of the SPE sorbent is a critical step to achieve high sensitivity, good reproducibility, and maximum analyte recovery, especially for complex sample matrices.
Why Is It Necessary to Dry the SPE Sorbent Before Elution?
How to Protect Your GC Column - Part 2
GCMSArticle | Academy

How to Protect Your GC Column - Part 2

How can you extend GC column lifetime and prevent contamination? Part 2 focuses on using liners with glass wool and proper column bake-out to maintain separation performance.
How to Protect Your GC Column - Part 2
How to Protect Your GC Column - Part 1
GCMSArticle | Academy

How to Protect Your GC Column - Part 1

Dirty samples can quickly damage your GC column and shorten its lifetime. Learn simple, proven ways to protect your column, improve performance, and reduce downtime. Part 1 focuses on smart sample preparation.
How to Protect Your GC Column - Part 1
SPE Troubleshooting - Extra Peak
LCMSGCMSArticle | Academy

SPE Troubleshooting - Extra Peak

An SPE technical tip focused on identifying the sources of interferences and extra peaks observed after sample extraction.
SPE Troubleshooting - Extra Peak