LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening
LCMSScientific article | Science and research

LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening

LCMS-Net is an end-to-end deep learning model for raw LC-HRMS data, improving accuracy, reducing preprocessing, and minimizing batch effects in metabolomics.
LCMS-Net: Deep Learning for Raw High Resolution Mass Spectrometry Data Applied to Forensic Cause-of-Death Screening
Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS
LCMSScientific article | Science and research

Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS

This study shows native protein stability in IMS-MS varies with ionization polarity, being higher when ionization matches solution-phase charge.
Investigating the Effect of Isoelectric Points on the Gas-Phase Stability of Native-like Proteins Analyzed in Positive- versus Negative-Ion Mode by IMS-MS
Analytica 2026: The Future of Chromatography Is Here – Are You Ready?
GCMSLCMSArticle | Events

Analytica 2026: The Future of Chromatography Is Here – Are You Ready?

Explore the future of chromatography at analytica 2026. Discover advances in sustainable LC, GC×GC, SFC, ion mobility and data-driven analytics shaping next-generation separation science workflows.
Analytica 2026: The Future of Chromatography Is Here – Are You Ready?
Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis
LCMSArticle | Environment

Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis

EU Drinking Water Directive 2020/2184 sets ultra-low limits for pesticides, PFAS, metals and endocrine disruptors. Learn how SPE and nitrogen evaporation enable LC-MS/MS compliance at ng/L levels.
Meeting EU Drinking Water Standards: The Critical Role of Sample Prep in Trace Contaminant Analysis
Revealing hidden chemicals at sea
LCMSGCMSArticle | Health

Revealing hidden chemicals at sea

Flame retardants were found throughout cruise ship interiors, with some areas showing much higher levels. A new RECETOX and NIVA study explores potential exposure risks for crew and passengers.
Revealing hidden chemicals at sea
Safe Sample Prep for PFAS Analysis: PTFE-Free Concentrators Explained
GCMSLCMSArticle | Science and research

Safe Sample Prep for PFAS Analysis: PTFE-Free Concentrators Explained

Organomation explains how PFAS-free nitrogen evaporators eliminate fluoropolymer contamination by replacing PTFE tape with a PTFE-free sealant, ensuring safe and reliable PFAS sample preparation.
Safe Sample Prep for PFAS Analysis: PTFE-Free Concentrators Explained
Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification
LCMSScientific article | Science and research

Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification

A validated QbD-based RP-HPLC method enables robust, stability-indicating impurity analysis of Elexacaftor, supporting process development and quality control in drug manufacturing.
Quality-by-Design-Driven RP-HPLC Method Development and Validation for Impurity Analysis of Elexacaftor, a Cystic Fibrosis Drug, with LC-MS/MS-Based Degradant Identification
Persistence-Directed Testing of Chemicals Discharged from Offshore Oil Platforms Combined with Nontargeted Analysis
GCMSLCMSScientific article | Science and research

Persistence-Directed Testing of Chemicals Discharged from Offshore Oil Platforms Combined with Nontargeted Analysis

A novel persistence-directed testing approach combined with nontarget GC-MS and LC-HRMS revealed a significant fraction of persistent chemicals in offshore oil platform produced waters.
Persistence-Directed Testing of Chemicals Discharged from Offshore Oil Platforms Combined with Nontargeted Analysis
The Critical Role of Nitrogen Blowdown in SPE Sample Preparation
LCMSGCMSArticle | Science and research

The Critical Role of Nitrogen Blowdown in SPE Sample Preparation

Explore how nitrogen blowdown enhances sample prep efficiency in SPE workflows using Waters Oasis, Agilent Bond Elut and Phenomenex Strata, improving analyte recovery, sensitivity and method reliability.
The Critical Role of Nitrogen Blowdown in SPE Sample Preparation
Accelerating High-Throughput Metabolomics: The Coupling of Biocrates MxP Quant 500 Kit and MICROVAP Plate Evaporator
LCMSArticle | Science and research

Accelerating High-Throughput Metabolomics: The Coupling of Biocrates MxP Quant 500 Kit and MICROVAP Plate Evaporator

Discover how combining the Biocrates MxP Quant 500 kit with the Organomation MICROVAP evaporator enables efficient, automated, and reproducible high-throughput metabolomics workflows.
Accelerating High-Throughput Metabolomics: The Coupling of Biocrates MxP Quant 500 Kit and MICROVAP Plate Evaporator