Novel fluorescent probe for real-time imaging of nascent DNA in live cells
ICPMSArticle | Scientific article

Novel fluorescent probe for real-time imaging of nascent DNA in live cells

Novel 2′-deoxycytidine triphosphate (dCTP) nucleotide modified with a thiazole orange fluorophore can be incorporated into DNA strand by DNA polymerases in vitro as well as in live cells.
Novel fluorescent probe for real-time imaging of nascent DNA in live cells
Scientists continue to push the boundaries of imaging techniques and reveal the mysterious world of molecules
GCMSICPMSLCMSArticle | Scientific article

Scientists continue to push the boundaries of imaging techniques and reveal the mysterious world of molecules

Scientists from the IOCB Prague, the Institute of Physics of the Czech Academy of Sciences, and Palacký University Olomouc, have successfully uncovered the mysteries of the world of molecules and atoms.
Scientists continue to push the boundaries of imaging techniques and reveal the mysterious world of molecules
Researchers at IOCB Prague develop a new method for enzymatic synthesis of potential RNA therapeutics
GCMSICPMSLCMSArticle | Science and research

Researchers at IOCB Prague develop a new method for enzymatic synthesis of potential RNA therapeutics

A team of researchers at IOCB Prague led by Prof. Michal Hock has developed a novel method for preparing ribonucleic acid (RNA) containing modified bases.
Researchers at IOCB Prague develop a new method for enzymatic synthesis of potential RNA therapeutics
Insight into the nucleosome recognition mechanisms
ICPMSArticle | Scientific article

Insight into the nucleosome recognition mechanisms

Scientists from IOCB Prague, Charles University, CEITEC, the Institute of Microbiology, and the University of Cologne studied the chromatin reader LEDGF and its association with methylated histone H3K36.
Insight into the nucleosome recognition mechanisms
Scientists from IOCB Prague have improved materials for reconstructive and plastic surgery
ICPMSArticle | Scientific article

Scientists from IOCB Prague have improved materials for reconstructive and plastic surgery

Researchers from IOCB Prague and Ghent University have been working on improving the properties of gelatin-based materials, thereby expanding the possibilities of their use mainly in medicine.
Scientists from IOCB Prague have improved materials for reconstructive and plastic surgery
Azopyrimidine photoswitches and their interactions with cyclodextrins
LCMSICPMSArticle | Scientific article

Azopyrimidine photoswitches and their interactions with cyclodextrins

Azopyrimidine photoswitches become encapsulated into β-cyclodextrin (CD) cavity selectively via their phenyl ring.
Azopyrimidine photoswitches and their interactions with cyclodextrins
What are the minimal folding seeds in proteins?
ICPMSArticle | Scientific article

What are the minimal folding seeds in proteins?

The scientists identified several tripeptides, which could be considered as folding seeds and might initiate the process of protein folding.
What are the minimal folding seeds in proteins?
Surface-mounted regular arrays of fullerene-based molecular rotors
ICPMSArticle | Scientific article

Surface-mounted regular arrays of fullerene-based molecular rotors

Scientists from IOCB Prague, the University of Colorado, and the University of Oxford prepared an array composed of a unique type of fullerene-based molecular rotors with a relatively high dipole moment.
Surface-mounted regular arrays of fullerene-based molecular rotors
Unique molecular CODE – Paramagnetic encoding of molecules
LCMSArticle | Science and research

Unique molecular CODE – Paramagnetic encoding of molecules

The principle of molecular coding created by Miloslav Polášek and his team at the IOCB Prague represents a new method on the border between the world of chemistry and modern technologies.
Unique molecular CODE – Paramagnetic encoding of molecules
IOCB Prague to contribute to a European project on the digitization of human body odors
GCMSArticle | Science and research

IOCB Prague to contribute to a European project on the digitization of human body odors

The SMELLODI project aims to create the prerequisites for the digitalization of human body odor. In the future, this could expand the possibilities of diagnosis or health monitoring.
IOCB Prague to contribute to a European project on the digitization of human body odors