TANDEM ION MOBILITY COUPLED WITH MASS SPECTROMETRY FOR GAS PHASE UNFOLDING STUDIES

Waters Cyclic IMS P20 Mass Spectrometer Insight—revealed, not inferred. Insight— revealed, not inferred Biological systems are inherently complex, and answering today’s research questions requires tools that can reveal that complexity with clarity. The Waters™ Cyclic™ IMS P20 Mass Spectrometer enables…

EXPANDING NATIVE MASS SPECTROMETRY CAPABILITIES FOR SOLUBLE AND MEMBRANE PROTEINS USING A QUADRUPOLE-ION MOBILITY-TIME-OF-FLIGHT MASS SPECTROMETRY SYSTEM Brad Williams1, Dale A. Cooper-Shepherd2, Mario Hensen3, Kleitos Sokratos3, Jonathan T.S. Hopper3, and James I. Langridge2 1. Waters Corporation, 34 Maple Drive, Milford,…

INVESTIGATING PRIMARY AND HIGHER-ORDER PROTEIN STRUCTURE ANALYSIS USING A NOVEL CYCLIC ION MOBILITY ENABLED QTOF PLATFORM Scott J. Berger1, Dale A. Cooper-Shepherd2 , Martin Palmer2, LeRoy B Martin1, Henry Shion1, and James I. Langridge2, 1 Waters Corporation, Milford, MA, 01757…

Application Note Structural Characterization of Glycated Monoclonal Antibodies Using Collision Induced Unfolding on the SELECT SERIES™ Cyclic™ IMS Mass Spectrometer Kristine Parson, Margo Wilson, Greg Adams, Jason Barker, Dale Cooper-Shepherd FUJIFILM Diosynth Biotechnologies, Waters Corporation Abstract Mass spectrometry-based methods are…