Verification of Quantitativity and Confirmation of Molecular Weight of Oligonucleotide therapeutics Using LCMS™-8060

Application News No. C215 LC-MS Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030  Overview Oligonucleotide therapeutics are synthetic oligonucleotides that demonstrate their medical efficacy through binding to target genes or target proteins…

C10G-E097 Oligonucleotide Therapeutics Solution Guide Types and Characteristics of Oligonucleotide Therapeutics Oligonucleotide therapeutics are nucleic acid polymers generally comprised of a few to several dozen bases However, it is a practical problem that oligonucleotide therapeutics are degraded and excreted rapidly…

High Performance Liquid Chromatograph Mass Spectrometer Application News Analysis of Oligonucleotide Impurities Using Single Quadrupole Mass Spectrometer Mizuki Hayakawa, Hiroyuki Niwa User Benefits  Combination use of LCMS-2050 single quadrupole mass spectrometer and LabSolutions Insight Biologics provides comprehensive characterization of…

Application News No. C219 Liquid Chromatography Mass Spectrometry Quantitative Analysis and Determination of Molecular Weight of siRNA Type Oligonucleotides by LCMS™-8060 „ Introduction „ SIM Chromatogram Nucleic acid drugs are synthetic oligonucleotides which are designed to bond specifically with target…