Development of simplified quantitative method for tryptic digested C-reactive protein by using online SPE coupled to triple quadrupole mass spectrometer

[ APPLICATION NOTE ] Sensitive and Reproducible LC-MS Quantification of C-Reactive Protein in Plasma: A Potential Biomarker of Inflammation Paula Orens, Mary Lame, Steven Calciano, and Erin Chambers Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION High sensitivity quantification of…

SENSITIVE AND REPRODUCIBLE LC-MS QUANTIFICATION OF C-REACTIVE PROTEIN IN PLASMA FOR CLINICAL RESEARCH Paula Orens, Mary Lame, Steven Calciano, and Erin Chambers Waters Corporation 34 Maple Street Milford, MA 01757 RESULTS INTRODUCTION Curve (µg/mL) Weighting Linear Fit (R2) % Accuracy…

[ TECHNOLOGY BRIEF ] Automated and Standardized, Kit-Based Workflow for Protein Quantification Mary Lame, Paula Orens, and Steven Calciano Waters Corporation, Milford, MA, USA Bottom-up, protein quantification workflows are time consuming and complex. A need exists for simpler and standardized…

C146-E286F Liquid Chromatograph Mass Spectrometer LCMS-8060 CHANGES EVERYTHING Sensitivity Speed Solutions LCMS-8060 The LCMS-8060 pushes the limits of what we can see. Creating the future of LC/MS/MS analysis can mean making something work with higher sensitivity, go faster or cost…