A Rapid UPLC-MS/MS Discovery Bioanalytical Method for the Quantification of Gefitinib and Four of Its Major Metabolites in Mouse Plasma

Application Note A Streamlined Workflow for Quantitative Bioanalysis using waters_connect for Quantitation Software: A Case Study Using Gefitinib Robert Plumb Waters Corporation, United States Published on November 20, 2025 Abstract Preclinical and early human drug metabolism and pharmacokinetics (DMPK) studies…

[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…

Application Note LipidQuan™: A Robust LC-MS/MS Methodology for Rapidly Profiling the Lipidome of Liver Tissue Following Metabolism of the Drug Gefitinib Nyasha Munjoma, I.D. Wilson, Lee A. Gethings, Robert S. Plumb Waters Corporation For research use only. Not for use…

Application Note Rapid Identification of Major Metabolites of Gefitinib Using Ion Mobility Enabled MS (HDMSE) with the SYNAPT XS Robert S. Plumb, Lauren Mullin, Adam King, Ian D. Wilson Waters Corporation, Computational and Systems Medicine, Imperial College Abstract This application…