Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape

Application Note Analytical Solutions and Method Development Considerations for Quantitative Bioanalytical Oligonucleotide Studies Marian Twohig, Catalin Doneanu, Margot Lee, Nikunj Tanna, Mary Trudeau Waters Corporation, United States Published on November 24, 2025 Abstract Oligonucleotide therapeutics are gaining momentum as innovative…

Application Note Rapid High Sensitivity LC-MS/MS Bioanalytical Method for the Simultaneous Quantification of Gefitinib Based PROTACs – 3 and Gefitinib in Rat Plasma to Support Discovery DMPK Studies Robert S. Plumb Waters Corporation This is an Application Brief and does…

[ APPLICATION NOTE ] Automating Sample Preparation Workflows for Hybrid LC-MS/MS Bioanalysis of Protein Therapeutics: Quantification of Etanercept Using Affinity Purification and Digestion Paula Orens and Mary Lame Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Automating a hybrid LC-MS/MS…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…