Evaluating BioAccord System Performance in Late Stage Development and QC Environment – Peptide Mapping Analysis

[ TECHNOLOGY BRIEF ] Evaluating BioAccord LC-MS System Performance for Deployment of a Compact, SmartMS-Enabled Biopharma Solution in Late Stage Development and QC Environment – Intact Mass Analysis Henry Shion, Jonathan Pugh, Jill Lord, Yun Alelyunas, Ying Qing Yu and…

[ TECHNOLOGY BRIEF ] Routine Peptide Mapping Analysis using the BioAccord System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA SmartMS-enabled BioAccord System improves the operational efficiency for routine peptide mapping analysis. GOAL Demonstrate how…

[ TECHNOLOGY BRIEF ] Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the BioAccord System Henry Shion, Ying Qing Yu, and Weibin Chen Waters Corporation, Milford, MA, USA Drug-to-Antibody Ratio (DAR) determination of Lys and Cys conjugated…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…