Novel MALDI-TOF MS Workflow for Ultrahigh-Throughput Screening of Different Analytes at Each Position on a Plate

High-throughput MALDI-MS based read-out of high-density droplet microarrays facilitating next generation on-chip drug discovery On-chip miniaturized and parallelized solution-based synthesis of novel compound libraries followed by on-chip characterization and screening in droplet microarrays has the potential to accelerate the drug…

Profiling mammalian cell differentiation by MALDI-TOF MS: Developing a highly reproducible and robust sample preparation workflow In this application note, we present a universal workflow for mammalian cell MALDI-TOF MS analysis in order to distinguish between ground-state naïve and differentiating…

Label-free compound profiling in K562 leukemia cells by MALDI-TOF mass spectrometry using heme B as response marker Bruker’s very fast rapifleX MALDI PharmaPulse solution has been successfully used in pharmaceutical research for compound screening in various cell-free biochemical assays that…

© Title Image - Analytik Jena Kinase inhibition screening by label-free mass spectrometry employing the MALDI PharmaPulse HTS solution Bruker´s MALDI PharmaPulse solution, integrating the rapifleX high-speed MALDI-TOF instrument with the dedicated MALDI PharmaPulse software suite, represents an emerging technology…