Accelerating GLP-1 Development with High- Throughput LC-MS Using the BioAccord™ LC MS System and the INTACT Mass Application

Application Note 100 Samples per Hour: High-Speed Oligonucleotide Analysis with BioAccord™ LC-MS and INTACT Mass Application Jonathan Fox, Laetitia Denbigh, Scott Berger, Kate Yu Waters Corporation, United States Published on November 27, 2025 Abstract The development of oligonucleotide therapeutics requires…

Application Note Higher Throughput Intact Mass Confirmation and Impurity Screening of GLP-1 Analogues Using Multi-Reflecting TOF Technology and INTACT Mass 1.9 Application Jonathan Fox, Scott J Berger, Laetitia Denbigh, Ying Qing Yu Waters Corporation, United States Published on July 14,…

Application Note Streamlined LC-MS Analysis of Stress Induced Impurities of a Synthetic Peptide using the BioAccord™ System and the waters_connect™ Intact Mass™ Application Nilini Ranbaduge, Henry Shion, Ying Qing Yu Waters Corporation Abstract This application note demonstrates the use of…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…