HILIC Analysis of CRISPR-Cas9 Gene Editing Tools on a Low Adsorption LC Flow Path

Application Note Biopharma/Pharma Determining mRNA Capping with HILIC-MS on a Low-Adsorption Flow Path Limiting interfering interactions with metal using the Agilent 1290 Infinity II Bio LC System Authors Gerd Vanhoenacker, Kris Morreel, Stefanie Jonckheere, Pat Sandra, and Koen Sandra RIC…

Application Note Biopharma mRNA Mapping with IP-RPLC-MS on a Low-Adsorption Flow Path Using an Agilent 1290 Infinity II Bio LC System Authors Abstract Helena Vanluchene, Kris Morreel, Jelle De Vos, Pat Sandra, and Koen Sandra RIC group, President Kennedypark 6,…

Application Note CRISPR Single Guide RNA Characterization by IP- RP-LC-MS with a Premier Oligonucleotide BEH 300 Å C18 Column Maissa M. Gaye, Chris Knowles, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation Abstract The high speed, low cost, and reduced need…

Application Note RNA Digestion Product Mapping Using an Integrated UPLC-MS and Informatics Workflow Catalin E. Doneanu, Chris Preston, Matt Gorton, Tatiana Johnson, Bala Addepalli, Ying Qing Yu Waters Corporation Abstract LC-MS analysis is an indispensable tool for single-guide RNA (sgRNA)…