Application of a Slotted Bandpass Ion Guide to Increase Robustness in Tandem Quadrupole LC-MS/MS Bioanalysis

Application Note Xevo TQ Absolute XR: Maximum Robustness and Sensitivity For High-Throughput Bioanalysis Robert S. Plumb Waters Corporation, United States Published on June 02, 2025 Contact Sales Abstract The accurate LC-MS/MS quantification of candidate pharmaceuticals, their metabolites and biomarkers in…

Application Note A Streamlined Workflow for Quantitative Bioanalysis using waters_connect for Quantitation Software: A Case Study Using Gefitinib Robert Plumb Waters Corporation, United States Published on November 20, 2025 Abstract Preclinical and early human drug metabolism and pharmacokinetics (DMPK) studies…

Tandem Quadrupole DESI Imaging To Visualize Spatial Distribution of Gefitinib and Related Metabolites in Rat Liver Anthony J. Midey,1 Robert Plumb,1 Nikunj Tanna,1 and Ian D. Wilson2 1Waters Corp., Milford, MA, USA; 2Imperial College London, London, UK Study Design Samples…

[ APPLICATION NOTEBOOK ] Versatile LC-MS/MS Solutions for the Evolving Bioanalysis Landscape Small Molecules Oligonucleotide Protein/Peptide Therapeutics Software Tools Targeted Imaging LC-MS/MS Solutions to Support Reliable, Sensitive and Efficient Workflows for the Bioanalysis of Drug Modalities Welcome to the Waters…