Determination of Tobramycin in Crude and In-Process Production Samples During Manufacturing Using HPAE-IPAD

Application Note 61 Determination of Tobramycin and Impurities Using HPAE-PAD INTRODUCTION Tobramycin is a water-soluble aminoglycoside antibiotic used in a variety of pharmaceutical applications, including ophthalmic and intravenous administrations.1 Tobramycin is purified from the fermentation of the actinomycete Streptomyces tenebrarius.…

Application Note 61 Determination of Tobramycin and Impurities Using HPAE-PAD INTRODUCTION Tobramycin is a water-soluble aminoglycoside antibiotic used in a variety of pharmaceutical applications, including ophthalmic and intravenous administrations.1 Tobramycin is purified from the fermentation of the actinomycete Streptomyces tenebrarius.…

APPLICATION UPDATE 72197 Determination of tobramycin using HPAE-IPAD on a compact ion chromatography system Authors Goal Terri Christison and Jeff Rohrer Thermo Fisher Scientific, Sunnyvale, CA To develop an HPAE-IPAD method for the determination of kanamycin A, kanamycin B, and…

Application Note 66 Determination of Neomycin B and Impurities Using HPAE-IPAD INTRODUCTION Neomycin is a complex of water-soluble aminoglycoside antibiotics purified from the fermentation of the actinomycete Streptomyces fradiae and used in a variety of pharmaceutical applications, including topical, ophthalmic,…