Determination of Neomycin B and Impurities Using HPAE-IPAD

Application Note 61 Determination of Tobramycin and Impurities Using HPAE-PAD INTRODUCTION Tobramycin is a water-soluble aminoglycoside antibiotic used in a variety of pharmaceutical applications, including ophthalmic and intravenous administrations.1 Tobramycin is purified from the fermentation of the actinomycete Streptomyces tenebrarius.…

Application Note 61 Determination of Tobramycin and Impurities Using HPAE-PAD INTRODUCTION Tobramycin is a water-soluble aminoglycoside antibiotic used in a variety of pharmaceutical applications, including ophthalmic and intravenous administrations.1 Tobramycin is purified from the fermentation of the actinomycete Streptomyces tenebrarius.…

Val Hanko and Jeff Rohrer Thermo Fisher Scientific, Sunnyvale, CA, USA Introduction Streptomycin is a water-soluble aminoglycoside antibiotic purified from the fermentation of the actinomycete Streptomyces griseus and used for intravenous administration1 to treat infections. Streptomycin must be determined and…

Application Note 186 Analysis of Paromomycin by HPAE-IPAD INTRODUCTION Paromomycin (Figure 1) is an aminoglycoside antibiotic produced by Streptomyces rimosus var. paromomycinus.1 The antibacterial spectrum of paromomycin is similar to other aminoglycosides that demonstrate broad spectrum activity against some gram-positive…