Determination of Tobramycin and Impurities Using HPAE-PAD

Application Note 61 Determination of Tobramycin and Impurities Using HPAE-PAD INTRODUCTION Tobramycin is a water-soluble aminoglycoside antibiotic used in a variety of pharmaceutical applications, including ophthalmic and intravenous administrations.1 Tobramycin is purified from the fermentation of the actinomycete Streptomyces tenebrarius.…

APPLICATION UPDATE 72197 Determination of tobramycin using HPAE-IPAD on a compact ion chromatography system Authors Goal Terri Christison and Jeff Rohrer Thermo Fisher Scientific, Sunnyvale, CA To develop an HPAE-IPAD method for the determination of kanamycin A, kanamycin B, and…

Application Note 66 Determination of Neomycin B and Impurities Using HPAE-IPAD INTRODUCTION Neomycin is a complex of water-soluble aminoglycoside antibiotics purified from the fermentation of the actinomycete Streptomyces fradiae and used in a variety of pharmaceutical applications, including topical, ophthalmic,…

Application Note 159 Determination of Sucralose Using HPAE-PAD INTRODUCTION Sucralose is used in the manufacture of nonnutritive sweetened food and beverage products. Sucralose, like most carbohydrates, lacks a good chromophore and therefore requires high concentrations to be detected by UV…