Purity, Assay, and Impurity Profiling of Single-Stranded Oligonucleotides Using Agilent Oligo Analysis Accelerator for OpenLab CDS

Application Note Biopharma Determination of Purity, Assay, and Impurity Profile for a Ligand-Conjugated Antisense Oligonucleotide Using Agilent Oligo Analysis Accelerator for OpenLab CDS Authors James Webster AstraZeneca Macclesfield, United Kingdom Brian Rivera Agilent Technologies, Inc. Santa Clara, CA, United States…

Application Note Automated LC/MS Quality Control of Anti-Sense Oligonucleotides Using purpose-built software and high-sensitivity single quadrupole detection Authors Brian Rivera, Lee Bertram Agilent Technologies, Inc. Abstract Antisense oligonucleotides (ASOs) are a complex class of therapeutic nucleic acids that require precise…

Application Note Biopharma Assessing the Purity of an Antisense Oligonucleotide Sample by LC/MS Using a high-sensitivity unit mass detector Authors Abstract Lee Bertram and Brian Rivera Agilent Technologies, Inc. This application note outlines a method for assessing the purity of…

Table of contents Fast Track to Certainty: Confident Biopharma Decisions with LC-Single Quadrupole Mass Detection How single quadrupole LC/MS simplifies identification, purification, and stability assessment in biopharma Table of Contents Introduction��������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������������� 3 Consolidating Biopharma QC Workflows: LC/UV Versus Single Quadrupole…