ADLM: QUANTIFICATION OF THYROGLOBULIN IN SERUM FOR CLINICAL RESEARCH USING SISCAPA WORKFLOW COMBINED WITH LC-MS/MS

QUANTIFICATION OF THYROGLOBULIN IN SERUM FOR CLINICAL RESEARCH USING SISCAPA WORKFLOW COMBINED WITH LC-MS/MS Dominic Foley1, Morteza Razavi2, Robert Wardle1, Mary Trudeau1, Nadim Mira1 and Lisa J Calton1 1) Waters Corporation, Wilmslow, Cheshire, UK. 2) SISCAPA Assay Technologies, Washington DC,…

Improving the Detection of Thyroglobulin in Human Plasma for Clinical Research by Combining SISCAPA Enrichment and Microflow LC-MS Jay S. Johnson,1 Morteza Razavi,2 James Murphy,1 Selena Larkin,2 and Paul Rainville1 1 Waters Corporation, Milford, MA, USA; 2 SISCAPA Assay Technologies,…

LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB Dominic Foley1, John Vukovic1, Dorothée Lebert2, Lisa J Calton1 1. Waters Corporation, Wilmslow, Cheshire, UK 2. Promise Proteomics, Grenoble, France INTRODUCTION Therapeutic monoclonal antibodies (t-mAbs) have…

B-155 LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB Dominic Foley1, John Vukovic1, Dorothée Lebert2, Lisa J Calton1 1. Waters Corporation, Wilmslow, Cheshire, UK 2. Promise Proteomics, Grenoble, France INTRODUCTION Therapeutic monoclonal antibodies (t-mAbs)…