Accelerating Oligonucleotide Research Using Novel Bioinert LC, QTOF and TQ LC-MS

C10G-E097 Oligonucleotide Therapeutics Solution Guide Types and Characteristics of Oligonucleotide Therapeutics Oligonucleotide therapeutics are nucleic acid polymers generally comprised of a few to several dozen bases However, it is a practical problem that oligonucleotide therapeutics are degraded and excreted rapidly…

A Software Workflow Using Wide Mass Range Single Quadrupole Mass Spectrometry Data Stream Applied to Oligonucleotides Confirmation Risa Suzuki1, 2, Kosuke Uchiyama2, Noriko Kato2, Yuka Fujito2, Jeffery Dahl1, Simon Ashton3, Neil Loftus3, Atsuhiko Toyama2, 4 1Shimadzu Scientific Instruments, Inc., Columbia,…

Measurement of Oligonucleotide Impurities/ LCMS-9030 Application News Measurement of Oligonucleotide Impurities Using Shimadzu Nexera XS Inert Coupled To LCMS-9030 QTOF Shannie Tay1, Derrick Tan1, Celine Sim2 1 Shimadzu Asia Pacific, Singapore 2 Nanyang Technological University, Singapore User Benefits  End-to-end…

Application News No. C215 LC-MS Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030  Overview Oligonucleotide therapeutics are synthetic oligonucleotides that demonstrate their medical efficacy through binding to target genes or target proteins…