AUTOMATING SUBUNIT MAB ATTRIBUTE SCREENING FOR IN-PROCESS MONITORING OF AN AUTOMATED HIGH-THROUGHPUT MULTI-PARALLEL BIOREACTOR

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

Application Note Monitoring Intact Glycoprofiles and Spent Media Metabolites in Samples from Sartorius Ambr 250 High Throughput Bioreactor System to Support Upstream Process Development Yun Wang Alelyunas, Charles Prochaska, Clint Kukla, Caitlin Dunning, Caitlin Hanna, Mark D. Wrona Waters Corporation,…

Application Note Similis Bio - Streamlined mAb Subunit LCMS Workflow for Multiple Attribute Monitoring of Biosimilar mAb Candidates During Bioprocessing and Development Samantha Ippoliti, Jared Young, Katy McNally, Caitlin Hanna, Ying Qing Yu, Bradley Prater, Mark D. Wrona, Emma Harry…

COMBINING INTACT GLYCOPROFILING AND CELL CULTURE MEDIA ANALYTICS FOR IN-PROCESS MONITORING OF AN AUTOMATED HIGH-THROUGHPUT MULTI-PARALLEL BIOREACTOR SYSTEM Authors: Yun Alelyunas1; Charles Prochaska2; Clint Kukla2; Guillaume Bechade3; Patrick Boyce3; Mark Wrona1 Affiliations: 1 Waters Corporation, Milford, MA; 2 Sartorius Stedim…