COMBINING INTACT GLYCOPROFILING AND CELL CULTURE MEDIA ANALYTICS FOR IN-PROCESS MONITORING OF AN AUTOMATED HIGH-THROUGHPUT MULTI-PARALLEL BIOREACTOR SYSTEM

Application Note Monitoring Intact Glycoprofiles and Spent Media Metabolites in Samples from Sartorius Ambr 250 High Throughput Bioreactor System to Support Upstream Process Development Yun Wang Alelyunas, Charles Prochaska, Clint Kukla, Caitlin Dunning, Caitlin Hanna, Mark D. Wrona Waters Corporation,…

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

Application Note Simplifying Bioreactor In-Process Monitoring with Waters Bioprocess Walk-Up Solutions Yun Wang Alelyunas, Elizabeth Embrey, Lindsay Collins, Adrien Pegaz-Blanc, Guillaume Mignard, Mark D. Wrona Waters Corporation This is an Application Brief and does not contain a detailed Experimental section.…

AUTOMATING SUBUNIT MAB ATTRIBUTE SCREENING FOR IN-PROCESS MONITORING OF AN AUTOMATED HIGH-THROUGHPUT MULTI-PARALLEL BIOREACTOR Nick Pittman1; Patrick Boyce1; Caitlin Hanna2; Samantha Ippoliti2; Yun W Alelyunas2; Charles Prochaska3; Clint Kukla3; Guillaume Bechade1; Magnus Wetterhall1; Mark Wrona2; Stephan M Koza2; Ying Qing…